Cryoablation leverages real-time imaging such as CT to monitor ice ball formation, enabling precise tumor targeting and controlled ablation, while preserving surrounding healthy lung tissue and vital structures, thus minimizing damage and complications.
Cryoablation is minimally invasive, causes mild postoperative pain, and supports fast recovery. It is suitable for elderly or frail patients and allows repeat treatments for recurrent or new tumors, offering high therapeutic flexibility.
The freezing process releases abundant tumor antigens that activate the patient’s immune system and enhance antitumor activity. Cryoablation also pairs well with chemotherapy, immunotherapy, radiotherapy, and other modalities to improve local and systemic outcomes.
References
Yang, W., et al. (2021). Co-ablation versus cryoablation for the treatment of stage III–IV non-small cell lung cancer: A prospective, noninferiority, randomized, controlled trial (RCT). Thoracic Cancer, 12(3), 475–483.
Castillo-Fortuño, À. (2025). Lung Cryoablation: Patient Selection, Techniques, and Outcomes. Radiographics, in press.
Niu L, Xu K, Mu F. Cryosurgery for lung cancer. J Thorac Dis. 2012 Aug;4(4):408-419. d
Chen, Y., et al. (2022). Cryoablation combined with PD-1 inhibitors for advanced solid tumors: A retrospective study. Frontiers in Immunology, 13, 966008.
(1) The lesion was close to chest wall. CT scan showed that the left upper lobe lung cancer was enlarged.
(2) After treatment by radioactive particles.
(3) No complication during and after procedure.
(1) The lesion was close to chest wall, and no injury of chest wall occurred .
(2) CT scan showed that there was a lesion at the junction of S4 and S5, sized as 15.1×11.8mm.
The article shared a case of percutaneous puncture treatment for small nodules in the inferior lobe of right lung with Cryosurgical System. Professor Zou Yinghua of Peking University First Hospital commented on the case.
The article shared a typical case of percutaneous puncture treatment for right lung metastasis of colorectal cancer with Cryosurgical System. Professor Li Xiaoguang of Beijing Hospital commented on the case.
The article shared a case of percutaneous puncture treatment for lung metastasis of liver cancer with Cryosurgical System. Professor Huang Jinhua, Sun Yat-sen University Cancer Center, commented on the case.
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